Hibernation-like cooling after stroke may reduce brain damage

medicalxpress - Our body loves the state of homeostasis, where everything is in perfect equilibrium, from temperature to pH levels to fluid balance. As soon as the body's core temperature drops below 95°F (35°C) and stays there for a long time, the heart, nervous system …

AI Summary: Researchers report that inducing a hibernation-like state via drugs and controlled cooling can reduce brain damage after ischemic stroke in preclinical and early clinical work, limiting infarct size, dampening inflammation and improving functional outcomes. The approach shows translational potential but requires carefully designed trials to confirm safety and efficacy.